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Physiome Sciences Inc jsim
Jsim, supplied by Physiome Sciences Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/jsim/jsim/pmc09014679-81-25-15
Average 90 stars, based on 1 article reviews
jsim - by Bioz Stars, 2026-09
90/100 stars

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Article Title: Hemodynamic and metabolic changes during hypercapnia with normoxia and hyperoxia using pCASL and TRUST MRI in healthy adults
Article Snippet: Dash et al. 2016 model can be downloaded (JSIM and Matlab code) from the NSR Physiome Project repository that contains integrative and descriptive models on human physiology: www.imagwiki.nibib.nih.gov/physiome/jsim/models/webmodel/NSR/SHbO2CO2Dash2016/ .

Article Title: Simulation environment and graphical visualization environment: a COPD use-case
Article Snippet: • JSim [9] is a tool developed within the National Simulation Resource Physiome project to run models written mainly in mathematical modelling language (MML), systems biology markup language (SBML) and CellML markup language.

Article Title: Simulation, identification and statistical variation in cardiovascular analysis (SISCA) - A software framework for multi-compartment lumped modeling.
Article Snippet: It has not yet been possible to obtain modeling approaches suitable for covering a wide range of real world scenarios in cardiovascular physiology because many of the system parameters are uncertain or even unknown.. Natural variability and statistical variation of cardiovascular system parameters in healthy and diseased conditions are characteristic features for understanding cardiovascular diseases in more detail.. This paper presents SISCA, a novel software framework for cardiovascular system modeling and its MATLAB implementation.

Article Title: Simulation environment and graphical visualization environment: a COPD use-case
Article Snippet: • JSim [ ] is a tool developed within the National Simulation Resource Physiome project to run models written mainly in mathematical modelling language (MML), systems biology markup language (SBML) and CellML markup language .

Concentration Assay:

Article Title: A theoretical framework for determining cerebral vascular function and heterogeneity from dynamic susceptibility contrast MRI
Article Snippet: .. The tissue concentration for each vessel generation (CtissueðtÞ) is calculated based on an arterial input function (AIF) obtained from Jsim (National Simulation Resource Physiome initiative).18 The vessels are approximated as cylindrical pipes with laminar flow. ..

Article Title: A theoretical framework for determining cerebral vascular function and heterogeneity from dynamic susceptibility contrast MRI
Article Snippet: .. The tissue concentration for each vessel generation ( C tissue ( t ) ) is calculated based on an arterial input function (AIF) obtained from Jsim (National Simulation Resource Physiome initiative). ..

Software:

Article Title: Evolution of mathematical models of cardiomyocyte electrophysiology.
Article Snippet: Advanced computational techniques and mathematical modeling have become more and more important to the study of cardiac electrophysiology.. In this review, we provide a brief history of the evolution of cardiomyocyte electrophysiology models and highlight some of the most important ones that had a major impact on our understanding of the electrical activity of the myocardium and associated transmembrane ion fluxes in normal and pathological states.. We also present the use of these models in the study of various arrhythmogenesis mechanisms, particularly the integration of experimental pharmacology data into advanced humanized models for in silico proarrhythmogenic risk prediction as an essential component of the Comprehensive in vitro Proarrhythmia Assay (CiPA) drug safety paradigm.

Generated:

Article Title: T2*-correction in dynamic contrast-enhanced MRI from double-echo acquisitions.
Article Snippet: .. Reference AIFs were generated in Jsim (www.physiome.org) and convolved according to Eq. ..



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KEY RESOURCES TABLE

Journal: Cell reports

Article Title: Transcriptional Circuit Fragility Influences HIV Proviral Fate

doi: 10.1016/j.celrep.2019.03.007

Figure Lengend Snippet: KEY RESOURCES TABLE

Article Snippet: JSim v2.15 (developed by the NSR Physiome Project) , Butterworth et al., 2013 ) https://www.physiome.org/jsim/ , RRID:SCR_007379.

Techniques: Western Blot, Virus, Recombinant, SYBR Green Assay, Reporter Assay, Luciferase, Bicinchoninic Acid Protein Assay, Membrane, Isolation, Transfection, Protease Inhibitor, Reverse Transcription, Cell Isolation, Purification, Plasmid Preparation, shRNA, Control, Clone Assay, Generated, Software